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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13320L | VU591 | Potassium Channel | |
1222810-74-3 | |||
T13320 | VU591 hydrochloride | Potassium Channel | |
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr... | |||
T70634 | Psycholeine | ||
Psycholeine is isolated from the tropical plant Psychotria oleoides; exhibits somatostatin antagonistic activity on growth hormone secretion. | |||
T23516 | VU590 | Potassium Channel | |
VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1).VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling. | |||
T62544 | MK-8153 | ||
MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 μM) and hERG EP (IC50: 34 μM).MK-8153 can be used as a diuretic. | |||
T12066 | MK-7145 | Others | |
MK-7145 is an inhibitor of ROMK(IC50 of 0.045 μM). | |||
T24623 | PF-06807656 | PF 06807656 | |
PF-06807656 is insensitive to the introduction of the N171D mutation in the ROMK conduction pore that greatly diminishes the activity of other small-molecule inhibitors. PF-06807656 is an effective ROMK inhibitor (Tl+ fl... | |||
T70636 | XAN35021 | ||
XAN35021, also known as ROMK inhibitor 25, or ROMK-IN-25, is a potent and selective ROMK inhibitor with improved pharmacokinetic properties. This product has no formal name at the moment. For the convenience of communic... | |||
T62760 | ROMK-IN-32 | ||
ROMK-IN-32 is an inhibitor of the extra-renal medullary potassium channel (ROMK) (IC50: 35 nM) and also inhibits hERG (IC50: 22 μM). |